Pulmonary arterial hypertension in familial hemiplegic migraine with ATP1A2 channelopathy

Pulmonary arterial hypertension in familial hemiplegic migraine with ATP1A2 channelopathy.

Cerveau et de L’Œil, Groupe Hospitalier Lariboisière – Fernand Widal, Paris, France ; 5 INSERM UMR_S 740, Université Paris Diderot, Sorbonne Paris Cité, Paris 6 Service de Neurologie, CHU de Limoges, Hôpital Dupuytren, Limoges, France; 7 Service de Cardiologie, CHU de Limoges, Hôpital Dupuytren, Limoges, France; 8 Unité Mixte de Recherche en Santé (UMR_S956), Université Pierre & Marie Curie (UP...

Familial Hemiplegic Migraine with Severe Attacks: A New Report with ATP1A2 Mutation

Introduction. Familial hemiplegic migraine (FHM) is a rare disorder characterized by migraine attacks with motor weakness during the aura phase. Mutations in CACNA1A, ATP1A2, SCN1A, and PRRT2 genes have been described. Methods. To describe a mutation in ATP1A2 gene in a FHM case with especially severe and prolonged symptomatology. Results. 22-year-old woman was admitted due to migraine-type hea...

Sporadic Hemiplegic Migraine with ATP1A2 and Prothrombin Gene Mutations

Background. Hemiplegic migraine is a rare type of migraine that may present in children and adolescents. Both familial and sporadic hemiplegic migraines have similar prevalence and clinical characteristics. Patient. We report an adolescent with sporadic hemiplegic migraine who previously had a similar attack in the past and who was initially evaluated for a possible acute ischemic event. Result...

Familial hemiplegic migraine.

[Familial hemiplegic migraine].

Familial hemiplegic migraine (FHM) is a rare subtype of migraine with aura. It is inherited as an autosomal dominant trait. A gene for FHM has been assigned to chromosome 19. This gene codes for a brain-specific calcium channel, and is responsible for FHM in 55% of the FHM families. Other FHM families have been linked to two different locations on chromosome 1. These locations contain possible ...